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The Autism Inpatient Collection

The NLMFF, in partnership with the Simons Foundation, is providing support for the Phase II application of the project entitled, “The Autism Inpatient Collection (AIC): Developing a Unique, Severely Affected Cohort To Accelerate Discovery and Targeted Treatment of Autism Subtypes.” Support from the Simons Foundation and the NLMFF in Phase I enabled Dr. Siegel to successfully work with his colleagues to launch the six-site collaborative and create the infrastructure for a uniquely valuable database of phenotypic and biological data to study patients at the severe end of the autism disorders spectrum. In Phase I, the collaborative collected critical data from over 300 patients and families across the six sites. This second phase of the project expands the cohort studied to a total of 1,600 probands and their families, providing an opportunity to document and investigate the full phenotypic range of Autism Spectrum Disorders, including those with the most severe challenging behaviors, communication and autism, thereby providing critical information to assist patients and their families.